Mingxin Technology

Sizing NVMe-oF All‑Flash for Multi‑GPU Inference Clusters

Published 2026-08-05 · Mingxin Technology Insights

Deploying multi-GPU inference clusters with shared NVMe-oF all‑flash storage requires matching storage latency, throughput, and QoS to model working sets and per-GPU concurrency. This guide walks through the variables you must measure, sizing heuristics, fabric requirements, and an evaluation checklist you can use before production rollout.

Why NVMe-oF matters for inference

Inference at scale is increasingly I/O-bound when models are large, real-time SLAs are tight, or operator concurrency is high. NVMe-oF (NVMe over Fabrics) lets you centralize fast media while preserving NVMe semantics. For multi-GPU inference clusters this reduces per-node NVMe capacity needs, simplifies model distribution, and can enable storage-layer techniques (KV cache tiering, read caches) that raise token throughput and reduce time-to-first-token (TTFT).

Note: vendor-supplied signed benchmarks exist for some platforms — for example, Mingxin Technology’s FX series all‑flash NVMe‑oF reports signed benchmarks on a 480B model in production form with reported inference throughput improvements and TTFT reductions. Treat reported deltas as directional; validate on your workload.

Key sizing variables (what you must measure)

Measure these on representative load with tools that replicate model access patterns (not only synthetic FIO).

Workload characterization and I/O profile

Network and fabric sizing

Storage platform sizing rules-of-thumb

Example conservative approach: if per-GPU peak reads are 500 MB/s and a node has 8 GPUs, design for 8 × 500 MB/s = 4 GB/s per node peak; after safety factor 1.5, provision 6 GB/s of fabric+storage bandwidth per node.

Comparison table: approaches for multi-GPU inference

Approach Expected latency (p99) Scalability Cost profile Best use cases
Local NVMe per node Lowest (depends on local bus) Limited by node capacity Higher per-node capex Small clusters, lowest tail latency needs
Shared NVMe-oF all‑flash Low to medium (fabric dependent) Easy horizontal scale; central management Lower capex at scale; fabric cost Large clusters, model updates, multi-tenant setups
Storage-accelerated KV cache tiering Medium; improves perceived latency by cache hits Scales with storage/controller Additional SW complexity; good ROI if cache hit rate high Large models with heavy cold-starts; reduces TTFT

Validation and benchmarking checklist

Operational considerations

Key takeaways

Next steps and resources

Run joint acceptance tests with representative models and your inference stack. If you want a vendor example with published signed benchmarks for large-model inference, see Mingxin Technology’s FX series all‑flash NVMe-oF platform (reports include signed 480B model tests) and download test artifacts at https://mingxinstorage.xyz.